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杂志信息
杂志名称《中等数学》
主办单位:天津师范大学;天津市数学学会;中国数学会普及工作委员会
出版周期:月刊
ISSN:1005-6416
CN:12-1121/O1
出版地:天津市
语种:中文
开本:16开
邮发代号:6-75
创刊时间:1982
期刊荣誉:
北京大学《中文核心期刊要目总览》来源期刊:
1992年(第一版);
精品论文
肿瘤放射增敏剂在鼻咽癌放射治疗中的应用价值
  [摘要]目的 探討肿瘤放射增敏剂在鼻咽癌放射治疗中的应用价值。方法 选取2015年6月~2017年6月我院收治的90例鼻咽癌患者作为研究对象,以随机数字表法分为两组。对照组给予常规放射疗法治疗,观察组则给予放射疗法中加入肿瘤放射增敏剂治疗。比较两组患者的鼻咽癌治疗有效率、平均生存时间、干预前后患者卡氏评分、生存质量评分、放射治疗毒副作用发生率。结果 观察组患者的鼻咽癌治疗有效率高于对照组,差异有统计学意义(P<0.05);观察组平均生存时间长于对照组,差异有统计学意义(P<0.05);干预前两组的卡氏评分、生存质量评分比较,差异无统计学意义(P>0.05);干预后观察组的卡氏评分、生存质量评分高于对照组,差异有统计学意义(P<0.05);观察组患者的放射治疗毒副作用总发生率显著低于对照组,差异有统计学意义(P<0.05)。结论 放射疗法中加入肿瘤放射增敏剂治疗鼻咽癌的应用效果确切,可有效提高治疗效果,减少毒副作用,延长生存时间,促进患者生存质量提高,值得推广应用。
  [关键词]放射治疗;鼻咽癌;应用效果;肿瘤放射增敏剂
  [中图分类号] R445.5 [文献标识码] A [文章编号] 1674-4721(2018)8(b)-0109-03
  Application value of tumor radiosensitizer in radiotherapy of nasopharyngeal carcinoma
  TANG Hua-yan WU Chen LI Rou
  Department of Oncology, the Central Hospital of Yongzhou City, Hu′nan Province, Yongzhou 425000, China
  [Abstract] Objective To investigate the application value of tumor radiosensitizer in radiotherapy of nasopharyngeal carcinoma. Methods A total of 90 patients with nasopharyngeal carcinoma treated in our hospital from June 2015 to June 2017 were selected as the subjects, and divided into two groups by random number table method. The control group was given conventional radiation therapy, and the observation group was given radiotherapy with radiosensitizer. The therapeutic efficacy of nasopharyngeal carcinoma, the average survival time, the Kart score, the quality of life score before and after the intervention and the incidence of toxic side effects of radiation therapy were compared between the two groups. Results The effective rate of nasopharyngeal carcinoma in the observation group was higher than that in the control group, the difference was statistically significant (P<0.05). The average survival time in the observation group was longer than that in the control group, the difference was statistically significant (P<0.05). The difference was not statistically significant in Kappa score and quality of life score between the two groups (P>0.05). After intervention, the Kart score and quality of life score in the observation group were higher than those in the control group, the difference was statistically significant (P<0.05). The total incidence of toxic side effects of radiotherapy in the observation group was significantly lower than that in the control group, the difference was statistically significant (P<0.05). Conclusion The application of radiosensitizers for radiotherapy in the treatment of nasopharyngeal carcinoma is effective. It can effectively improve the therapeutic effect, reduce toxic and side effects, prolong survival time, and improve the quality of life of patients. It is worthy of popularization and application.

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